To refine the Immortal Spirit Pill, the most important thing of course is the ingredients needed for alchemy.
Nowadays, the Ancient Martial World is far inferior to the past, not like in the Ancient Times, now the rare treasures of heaven and earth are extremely scarce. Take the Immortal Spirit Fruit for example, although it was uncommon in the Ancient Times, at least it could be discovered from time to time, and even cultivated in the Skies Beyond the Skies.
Undoubtedly, the Immortal Spirit Fruit is the best ingredient for refining the Immortal Spirit Pill.
Of course, if there is absolutely no Immortal Spirit Fruit, other ingredients can be used as replacements, but the effect will not be as good, and the difficulty of refining will greatly increase.
